Published Paper

1. Colorectal Cancer

FKL Chan, MCS Wong, AT Chan, JE East, HM Chiu, GK Makharia, D Weller, CJ Ooi, J Limsrivilai, Y Saito, DV Hang, JD Emery, D Makmun, KC Wu, RAR Ali, and SC NgJoint Asian Pacific Association of Gastroenterology (Apage)-Asian Pacific Society of Digestive Endoscopy (Apsde) Clinical Practice Guidelines on the Use of Non-Invasive Biomarkers for Diagnosis of Colorectal Neoplasia. 07, 2023.Gut: p. 15 [IF: 23.1]

JQ Liang, Y Zeng, G Kwok, CP Cheung, BY Suen, JYL Ching, KF To, J Yu, FKL Chan, and SC NgNovel Microbiome Signatures for Non-Invasive Diagnosis of Adenoma Recurrence after Colonoscopic Polypectomy. 04, 2022.Alimentary Pharmacology and Therapeutics 55(7): p. 847-855 [IF: 6.6]

JQ Liang, T Li, G Nakatsu, YX Chen, TO Yau, E Chu, S Wong, CH Szeto, SC Ng, FKL Chan, JY Fang, JJY Sung, and J Yu, A Novel Faecal Lachnoclostridium Marker for the Non-Invasive Diagnosis of Colorectal Adenoma and Cancer. 11, 2019.Gut [IF: 23.1]

Q Liang, J Chiu, Y Chen, Y Huang, A Higashimori, J Fang, H Brim, H Ashktorab, SC Ng, SSM Ng, S Zheng, FKL Chan, JJY Sung, and J Yu, Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer. 04, 2017.Clinical Cancer Research 23: p. 2061-2070 [IF: 10.4]

J Yu, Q Feng, SH Wong, D Zhang, QY Liang, Y Qin, L Tang, H Zhao, J Stenvang, Y Li, X Wang, X Xu, N Chen, WK Wu, J Al-Aama, HJ Nielsen, P Kiilerich, BA Jensen, TO Yau, Z Lan, H Jia, J Li, L Xiao, TY Lam, SC Ng, AS Cheng, VW Wong, FK Chan, H Yang, L Madsen, C Datz, H Tilg, J Wang, N Brunner, K Kristiansen, M Arumugam, and JJ Sung, Metagenomic Analysis of Faecal Microbiome as a Tool Towards Targeted Non-Invasive Biomarkers for Colorectal Cancer. 01, 2017.Gut 66(1): p. 70-78 [IF: 23.1]

2. Autism

Y Wan, OWH Wong, HM Tun, Q Su, Z Xu, W Tang, SL Ma, S Chan, FKL Chan, and SC NgFecal Microbial Marker Panel for Aiding Diagnosis of Autism Spectrum Disorders. 10, 2024.Gut Microbes 16(1): p. 2418984 [IF: 12.2]

Q Su, OWH Wong, WQ Lu, YT Wan, L Zhang, WY Xu, MKT Li, CY Liu, CP Cheung, JYL Ching, PK Cheong, TF Leung, SD Chan, P Leung, FKL Chan, and SC NgMultikingdom and Functional Gut Microbiota Markers for Autism Spectrum Disorder. 09, 2024.Nature Microbiology 9(9): p. 26 [IF: 20.5]

Wan, Q Su, and SC NgNew Insights on Gut Microbiome and Autism. 07, 2024.Trends in Molecular Medicine [IF: 12.8]

Y Wan, L Zhang, Z Xu, Q Su, TF Leung, D Chan, OWH Wong, S Chan, FKL Chan, HM Tun, and SC NgAlterations in Fecal Virome and Bacteriome Virome Interplay in Children with Autism Spectrum Disorder. 02, 2024.Cell Reports Medicine 5(2) [IF: 11.7]

YT Wan, T Zuo, ZL Xu, F Zhang, H Zhan, D Chan, TF Leung, YK Yeoh, FKL Chan, R Chan, and SC Ng, Underdevelopment of the Gut Microbiota and Bacteria Species as Non-Invasive Markers of Prediction in Children with Autism Spectrum Disorder. 05, 2022.Gut 71(5): p. 910-918 [IF: 23.1]

3. Inflammatory Bowel Disease

  1. J Zheng, Q Sun, M Zhang, C Liu, Q Su, L Zhang, Z Xu, W Lu, J Ching, W Tang, CP Cheung, AL Hamilton, AL Wilson O'Brien, SC Wei, CN Bernstein, DT Rubin, EB Chang, M Morrison, MA Kamm, FKL Chan, J Zhang, and SC NgNoninvasive, Microbiome-Based Diagnosis of Inflammatory Bowel Disease. 10, 2024.Nature Medicine [IF: 58.7]

  2. CY Wu, LL Liang, HJ Ho, CT Hsu, HT Hsu, CK Ao, CY Wu, YH Lin, YF Chuang, YC Hsu, YJ Chen, and SC NgPhysical Fitness and Inflammatory Bowel Disease Risk among Children and Adolescents in Taiwan. 06, 2023.JAMA Pediatr 177(6): p. 608-616 [IF: NA]

  3. JWY Mak, Y Sun, J Limsrivilai, M Abdullah, J Kaibullayeva, D Balderramo, BI Vergara, MS Paudel, R Banerjee, I Hilmi, RAR Ali, SC Wei, KK Ng, M Altuwaijri, P Kelly, JK Yamamoto-Furusho, PG Kotze, V Ahuja, VH Chong, HV Dao, Y Abbey, JYL Ching, A Ho, AKW Chan, CN Bernstein, RB Gearry, M Abreu, DT Rubin, I Dotan, L Hracs, GG Kaplan, and SC NgDevelopment of the Global Inflammatory Bowel Disease Visualization of Epidemiology Studies in the 21(St) Century (Gives-21). 05, 2023.BMC Med. Res. Methodol. 23(1): p. 129 [IF: BMC Med. Res. Methodol.]

  4. SM Lin, LH Lau, N Chanchlani, NA Kennedy, and SC NgRecent Advances in Clinical Practice: Management of Inflammatory Bowel Disease During the Covid-19 Pandemic. 04, 2022.Gut: p. 14 [IF: 23.1]

  5. JWY Mak, NTK Yuen, TCF Yip, RHM Lam, BKH Lam, CTY Cheng, GLH Wong, FKL Chan, and SC NgNo Increased Risk of Flare in Ulcerative Colitis Patients in Corticosteroid-Free Remission after Stopping 5-Aminosalicylic Acid: A Territory-Wide Population-Based Study. 04, 2022.Journal of Gastroenterology and Hepatology: p. 6 [IF: 3.7]

  6. JY Zheng, QR Sun, JW Zhang, and SC NgThe Role of Gut Microbiome in Inflammatory Bowel Disease Diagnosis and Prognosis. 12, 2022.United European Gastroenterology Journal 10(10): p. 1091-1102 [IF: 5.8]

  7. X Zhilu, D Xiangqian, Y Keli, C Caroline, Z Jingwan, L Yu, Z Tao, CL Cheung, S Yang, Z Fengrui, CF Kl, SJ Jy, Y Jun, B Anthony, B Nicolas, C Jean-Frederic, WS Hei, M Yinglei, and CN Siew, Association of Adherent-Invasive Escherichia Coli with Severe Gut Mucosal Dysbiosis in Hong Kong Chinese Population with Crohn's Disease. 11, 2021.Gut Microbes 13(1) [IF: 12.2]

  8. JWY Mak, C Lok Tung Ho, K Wong, TY Cheng, TCF Yip, WK Leung, M Li, FH Lo, KM Ng, SF Sze, CM Leung, SWC Tsang, EHS Shan, KH Chan, BCY Lam, AJ Hui, WH Chow, and SC NgEpidemiology and Natural History of Elderly-Onset Inflammatory Bowel Disease: Results from a Territory-Wide Hong Kong Ibd Registry. 03, 2021.Journal of Crohn's & Colitis 15(3): p. 401-408 [IF: 8.3]

  9. J Zhang, EC Hoedt, Q Liu, E Berendsen, JJ Teh, A Hamilton, OB AW, JYL Ching, H Wei, K Yang, Z Xu, SH Wong, JWY Mak, JJY Sung, M Morrison, J Yu, MA Kamm, and SC NgElucidation of Proteus Mirabilis as a Key Bacterium in Crohn's Disease Inflammation. 01, 2021.Gastroenterology 160(1): p. 317-330.e11 [IF: 26.3]

  10. R Banerjee, P Pal, JWY Mak, and SC NgChallenges in the Diagnosis and Management of Inflammatory Bowel Disease in Resource-Limited Settings in Asia. 12, 2020.Lancet Gastroenterology & Hepatology 5(12): p. 1076-1088 [IF: 30.9]

  11. J Limsrivilai, CK Lee, P Prueksapanich, K Harinwan, A Sudcharoen, N Cheewasereechon, S Aniwan, P Sripongpan, P Wetwittayakhlang, A Pongpaibul, A Sanpavat, N Pausawasdi, P Charatcharoenwitthaya, PDR Higgins, and SC NgValidation of Models Using Basic Parameters to Differentiate Intestinal Tuberculosis from Crohn's Disease: A Multicenter Study from Asia. 12, 2020.PLoS One 15(11): p. e0242879 [IF: 2.9]

  12. SC Ng, JWY Mak, P Pal, and R Banerjee, Optimising Management Strategies of Inflammatory Bowel Disease in Resource-Limited Settings in Asia. 12, 2020.Lancet Gastroenterology & Hepatology 5(12): p. 1089-1100 [IF: 30.9]

  13. SC Ng, JWY Mak, L Hitz, Y Chowers, CN Bernstein, and MS Silverberg, Covid-19 Pandemic: Which Ibd Patients Need to Be Scoped-Who Gets Scoped Now, Who Can Wait, and How to Resume to Normal. 10, 2020.Journal of Crohn's & Colitis 14(Supplement_3): p. S791-s797 [IF: 8.3]

  14. JWY Mak, MT Weng, SC Wei, and SC NgZero Covid-19 Infection in Inflammatory Bowel Disease Patients: Findings from Population-Based Inflammatory Bowel Disease Registries in Hong Kong and Taiwan. 06, 2020.Journal of Gastroenterology and Hepatology [IF: 3.7]

  15. AN Ananthakrishnan, GG Kaplan, and SC NgChanging Global Epidemiology of Inflammatory Bowel Diseases: Sustaining Health Care Delivery into the 21st Century. 01, 2020.Clinical Gastroenterology and Hepatology [IF: 11.6]

  16. JWY Mak, W Tang, TCF Yip, ZH Ran, SC Wei, V Ahuja, S Kumar, WK Leung, I Hilmi, J Limsrivilai, S Aniwan, BCY Lam, KH Chan, KM Ng, CM Leung, MKK Li, FH Lo, ASF Sze, SWC Tsang, AJ Hui, JL Hartono, and SC NgStopping Anti-Tumour Necrosis Factor Therapy in Patients with Perianal Crohn's Disease. 12, 2019.Alimentary Pharmacology and Therapeutics 50(11-12): p. 1195-1203 [IF: 6.6]

  17. T Zuo, XJ Lu, Y Zhang, CP Cheung, S Lam, F Zhang, W Tang, JYL Ching, R Zhao, PKS Chan, JJY Sung, J Yu, FKL Chan, Q Cao, JQ Sheng, and SC NgGut Mucosal Virome Alterations in Ulcerative Colitis. 07, 2019.Gut 68(7): p. 1169-1179 [IF: 23.1]

  18. SC Ng and AN Ananthakrishnan, New Approaches Along the Ibd Course: Diet, Tight Control and Stem Cells. 02, 2019.Nature Reviews Gastroenterology & Hepatology 16(2): p. 82-84 [IF: 46.4]

  19. WY Mak, OS Mak, CK Lee, W Tang, WK Leung, MTL Wong, ASF Sze, M Li, CM Leung, FH Lo, BCY Lam, KH Chan, EHS Shan, SWC Tsang, AJ Hui, WH Chow, FKL Chan, JJY Sung, and SC NgSignificant Medical and Surgical Morbidity in Perianal Crohn's Disease: Results from a Territory-Wide Study. 12, 2018.Journal of Crohn's & Colitis 12(12): p. 1392-1398 [IF: 8.3]

  20. SC Ng, GG Kaplan, W Tang, R Banerjee, B Adigopula, FE Underwood, D Tanyingoh, SC Wei, WC Lin, HH Lin, J Li, S Bell, O Niewiadomski, MA Kamm, Z Zeng, M Chen, P Hu, D Ong, CJ Ooi, KL Ling, Y Miao, J Miao, HJ de Silva, M Niriella, S Aniwan, J Limsrivilai, P Pisespongsa, K Wu, H Yang, KK Ng, HH Yu, Y Wang, Q Ouyang, M Abdullah, M Simadibrata, J Gunawan, I Hilmi, KL Goh, Q Cao, H Sheng, A Ong-Go, VH Chong, JYL Ching, JCY Wu, FKL Chan, and JJY Sung, Population Density and Risk of Inflammatory Bowel Disease: A Prospective Population-Based Study in 13 Countries or Regions in Asia-Pacific. 09, 2018.American Journal of Gastroenterology 114(1): p. 107-115 [IF: 8.5]

  21. HY Shi and SC NgThe State of the Art on Treatment of Crohn's Disease. 09, 2018.Journal of Gastroenterology 53(9): p. 989-998 [IF: 6.9]

  22. T Zuo and SC NgThe Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease. 09, 2018.Frontiers in Microbiology 9: p. 2247 [IF: 4]

  23. T Zuo, MA Kamm, JF Colombel, and SC NgUrbanization and the Gut Microbiota in Health and Inflammatory Bowel Disease. 07, 2018.Nature Reviews Gastroenterology & Hepatology 15(7): p. 440-452 [IF: 46.4]

  24. WKK Wu, R Sun, T Zuo, Y Tian, Z Zeng, J Ho, JCY Wu, FKL Chan, MTV Chan, J Yu, JJY Sung, SH Wong, MH Wang, and SC NgA Novel Susceptibility Locus in Mst1 and Gene-Gene Interaction Network for Crohn's Disease in the Chinese Population. 04, 2018.Journal of Cellular and Molecular Medicine 22(4): p. 2368-2377 [IF: 4.3]

  25. CM Leung, W Tang, M Kyaw, G Niamul, S Aniwan, J Limsrivilai, YF Wang, Q Ouyang, M Simadibrata, M Abdullah, DE Ong, HH Yu, J Zhang, J Ching, JCY Wu, FKL Chan, JJY Sung, and SC NgEndoscopic and Histological Mucosal Healing in Ulcerative Colitis in the First Year of Diagnosis: Results from a Population-Based Inception Cohort from Six Countries in Asia. 12, 2017.Journal of Crohn's & Colitis 11(12): p. 1440-1448 [IF: 8.3]

  26. SC Ng, HY Shi, N Hamidi, FE Underwood, W Tang, EI Benchimol, R Panaccione, S Ghosh, JCY Wu, FKL Chan, JJY Sung, and GG Kaplan, Worldwide Incidence and Prevalence of Inflammatory Bowel Disease in the 21st Century: A Systematic Review of Population-Based Studies. 12, 2017.Lancet 390(10114): p. 2769-2778 [IF: 98.4]

  27. HY Shi, FKL Chan, AWH Chan, A Higashimori, M Kyaw, JYL Ching, AKC Luk, SH Wong, JCY Wu, JJY Sung, and SC NgAccuracy of Fecal Immunochemical Test to Predict Endoscopic and Histological Healing in Ulcerative Colitis: A Prospective Study Based on Validated Histologic Scores. 09, 2017.Journal of Crohn's & Colitis 11(9): p. 1071-1077 [IF: 8.3]

  28. JKY Hooi, WY Lai, WK Ng, MMY Suen, FE Underwood, D Tanyingoh, P Malfertheiner, DY Graham, VWS Wong, JCY Wu, FKL Chan, JJY Sung, GG Kaplan, and SC NgGlobal Prevalence of Helicobacter Pylori Infection: Systematic Review and Meta-Analysis. 08, 2017.Gastroenterology 26: p. 26 [IF: 26.3]

  29. GG Kaplan and SC NgUnderstanding and Preventing the Global Increase of Inflammatory Bowel Disease. 02, 2017.Gastroenterology 152: p. 313-321.e2 [IF: 26.3]

  30. K Farkas, H Chan, M Rutka, Z Szepes, F Nagy, L Tiszlavicz, T Nyari, W Tang, G Wong, R Tang, A Lo, C Cheung, S Wong, R Lui, T Molnar, and SC NgGastroduodenal Involvement in Asymptomatic Crohn's Disease Patients in Two Areas of Emerging Disease: Asia and Eastern Europe. 12, 2016.Journal of Crohn's & Colitis 10(12): p. 1401-1406 [IF: 8.3]

  31. GG Kaplan and SC NgGlobalisation of Inflammatory Bowel Disease: Perspectives from the Evolution of Inflammatory Bowel Disease in the Uk and China. 12, 2016.Lancet Gastroenterology & Hepatology 1(4): p. 307-316 [IF: 30.9]

  32. SC Ng, WK Leung, HY Shi, MKK Li, CM Leung, CKM Ng, FH Lo, YT Hui, SWC Tsang, YK Chan, CK Loo, KH Chan, AJ Hui, WH Chow, M Harbord, JYL Ching, M Lee, V Chan, W Tang, IFN Hung, J Ho, WC Lao, MTL Wong, SF Sze, EHS Shan, BCY Lam, RWH Tong, LY Mak, SH Wong, JCY Wu, FKL Chan, and JJY Sung, Epidemiology of Inflammatory Bowel Disease from 1981 to 2014: Results from a Territory-Wide Population-Based Registry in Hong Kong. 08, 2016.Inflammatory Bowel Diseases 22(8): p. 1954-1960 [IF: 4.5]

  33. HY Shi, FKL Chan, WK Leung, MKK Li, CM Leung, SF Sze, JYL Ching, FH Lo, SWC Tsang, EHS Shan, LY Mak, BCY Lam, AJ Hui, WH Chow, MTL Wong, IFN Hung, YT Hui, YK Chan, KH Chan, CK Loo, CKM Ng, WC Lao, M Harbord, JCY Wu, JJY Sung, and SC NgLow-Dose Azathioprine Is Effective in Maintaining Remission in Steroid-Dependent Ulcerative Colitis: Results from a Territory-Wide Chinese Population-Based Ibd Registry. 07, 2016.Therapeutic Advances in Gastroenterology 9(4): p. 449-456 [IF: 3.9]

  34. AHC Bai, WKK Wu, L Xu, SH Wong, MY Go, AWH Chan, M Harbord, S Zhang, M Chen, JCY Wu, MWY Chan, MTV Chan, FKL Chan, JJY Sung, J Yu, ASL Cheng, and SC NgDysregulated Lysine Acetyltransferase 2b Promotes Inflammatory Bowel Disease Pathogenesis through Transcriptional Repression of Interleukin-10. 06, 2016.Journal of Crohn's & Colitis 10(6): p. 726-734 [IF: 8.3]

  35. WK Ng, SH Wong, and SC NgChanging Epidemiological Trends of Inflammatory Bowel Disease in Asia. 04, 2016.Intestinal Research 14: p. 111-9 [IF: 3.4]

  36. SC NgEmerging Trends of Inflammatory Bowel Disease in Asia. 03, 2016.Gastroenterology and Hepatology 12: p. 193-196 [IF: NA]

  37. AN Ananthakrishnan, HY Shi, W Tang, CC Law, JJ Sung, FK Chan, and SC NgSystematic Review and Meta-Analysis: Phenotype and Clinical Outcomes of Older-Onset Inflammatory Bowel Disease. 02, 2016.Journal of Crohn's & Colitis 10(10): p. 1224-36 [IF: 8.3]

  38. HY Shi, FK Chan, WK Leung, MK Li, CM Leung, SF Sze, JY Ching, FH Lo, SW Tsang, EH Shan, LY Mak, BC Lam, AJ Hui, SH Wong, MT Wong, IF Hung, YT Hui, YK Chan, KH Chan, CK Loo, RW Tong, WH Chow, CK Ng, WC Lao, M Harbord, JC Wu, JJ Sung, and SC NgNatural History of Elderly-Onset Ulcerative Colitis: Results from a Territory-Wide Inflammatory Bowel Disease Registry. 02, 2016.Journal of Crohn's & Colitis 10(2): p. 176-185 [IF: 8.3]

  39. SC Ng, Z Zeng, O Niewiadomski, W Tang, S Bell, MA Kamm, P Hu, HJ De Silva, MA Niriella, WSAAY Udara, D Ong, KL Ling, CJ Ooi, I Hilmi, K Lee Goh, Q Ouyang, YF Wang, K Wu, X Wang, P Pisespongsa, S Manatsathit, S Aniwan, J Limsrivilai, J Gunawan, M Simadibrata, M Abdullah, SWC Tsang, FH Lo, AJ Hui, CM Chow, HH Yu, MF Li, KK Ng, JYL Ching, V Chan, JCY Wu, FKL Chan, M Chen, and JJY Sung, Early Course of Inflammatory Bowel Disease in a Population-Based Inception Cohort Study from 8 Countries in Asia and Australia. 01, 2016.Gastroenterology 150(1): p. 86-95.e3 [IF: 26.3]

  40. SC Ng, W Tang, RW Leong, M Chen, Y Ko, C Studd, O Niewiadomski, S Bell, MA Kamm, HJ De Silva, A Kasturiratne, YU Senanayake, CJ Ooi, KL Ling, D Ong, KL Goh, I Hilmi, Q Ouyang, YF Wang, P Hu, Z Zhu, Z Zeng, K Wu, X Wang, B Xia, J Li, P Pisespongsa, S Manatsathit, S Aniwan, M Simadibrata, M Abdullah, SWC Tsang, TC Wong, AJ Hui, CM Chow, HH Yu, MF Li, KK Ng, J Ching, JCY Wu, FKL Chan, and JJY Sung, Environmental Risk Factors in Inflammatory Bowel Disease: A Population-Based Case-Control Study in Asia-Pacific. 07, 2015.Gut 64(7): p. 1063-1071 [IF: 23.1]

  41. SC Ng, W Tang, RW Leong, M Chen, Y Ko, C Studd, O Niewiadomski, S Bell, MA Kamm, HJ De Silva, A Kasturiratne, YU Senanayake, CJ Ooi, KL Ling, D Ong, KL Goh, I Hilmi, Q Ouyang, YF Wang, P Hu, Z Zhu, Z Zeng, K Wu, X Wang, B Xia, J Li, P Pisespongsa, S Manatsathit, S Aniwan, M Simadibrata, M Abdullah, SWC Tsang, TC Wong, AJ Hui, CM Chow, HH Yu, MF Li, KK Ng, J Ching, JCY Wu, FKL Chan, and JJY Sung, Environmental Risk Factors in Inflammatory Bowel Disease: A Population-Based Case-Control Study in Asia-Pacific. 07, 2015.Gut 64(7): p. 1063-1071 [IF: 23.1]

  42. SC Ng, CN Bernstein, MH Vatn, PL Lakatos, EV Loftus Jr, C Tysk, C O'Morain, B Moum, and JF Colombel, Geographical Variability and Environmental Risk Factors in Inflammatory Bowel Disease. 04, 2013.Gut 62(4): p. 630-649 [IF: 23.1]

  43. SC Ng, JL Benjamin, NE McCarthy, CRH Hedin, A Koutsoumpas, S Plamondon, CL Price, AL Hart, MA Kamm, A Forbes, SC Knight, JO Lindsay, K Whelan, and AJ Stagg, Relationship between Human Intestinal Dendritic Cells, Gut Microbiota, and Disease Activity in Crohn's Disease. 10, 2011.Inflammatory Bowel Diseases 17(10): p. 2027-2037 [IF: 4.5]