G-NiiB Geniebiome

Transform lives with microbial diagnostics

Our platform technologies are driving new solutions for early disease detection

Discovery Platform

MicroSigX holds a comprehensive and unique databank for unparalleled microbiome discoveries and insights

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1. Comprehensive clinical samples with metadata
Over 8,000 consistently analysed stool samples with over 1000 longitudinal metadata points per sample in health and diseases.
2. Advanced bioinformatic and AI-driven analysis
Deep metagenomic analysis coupled with machine-learning models to identify species, strains, genes and functional pathways across eight common diseases to inform product development
3. Discovery of disease-specific and highly accurate microbial signatures
Identify reliable signals by combining in-house and public profiles to achieve the most consistent microbial taxonomy and functional insights
4. Integrative analysis of host-microbe relationships
Extensive metadata including medical history, drugs, diet and lifestyle enables robust insights into identification of truly health- or disease-promoting associated species
5. Partnership with world-leading R & D Centers
Close partnership with the Microbiota-I Center (MagIC) to continuously expand the databank for data-driven discovery and product opportunities
Diagnostic Platform

“Our proprietary microbial biomarkers are non-invasive, biologically relevant, and disease-specific.”

MicroSigX’s biomarker discovery platform utilizes in-depth metagenomic analysis of large human microbial datasets and in-house proprietary machine-learning approaches to identify microbiome signatures specific to different human diseases with high accuracy

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1. Advanced sequencing and proprietary algorithms
MicroSigX’s core diagnostic technology transforms metagenomic-sequencing derived-microbial signals into proprietary algorithms to predict risk of diseases
2. At-home stool sample collection
Simple sampling method preserves quality of microbial community profile at room temperature, ensuring convenient storage and transport
3. Development of PCR-based technologies for disease risk assessment
Transforming untargeted metagenomic detection into targeted-PCR approaches and optimizing PCR technologies for maximum accuracy
4. Discovery, validation and real-life testing
MicroSigX’s patented core PCR and metagenomics technologies have been extensively validated, demonstrating unparalleled performance in multiple validation and real-life settings. Some of these technologies are poised to enter clinical trials for regulatory approval as first-in-class in vitro diagnostics.

MICROSIGX’s pioneering diagnostic technology is transforming the detection and understanding of microbiome-related diseases, enabling earlier, more accurate, and non-invasive approaches to improving human health.