MICROBIAL DIAGNOSTICS

Our proprietary microbial biomarkers are non-invasive, biologically relevant, and disease-specific.

MicroSigX’s biomarker discovery platform leverages in-depth metagenomic dataset of human microbiome and in-house proprietary machine learning approaches to identify microbiome signatures targeting different human diseases. The gut microbiome is a valuable source of biologically relevant biomarkers that can be transformed into precise diagnostic and prognostic tools. Clinicians can utilize these non-invasive tools for early disease detection and monitoring to optimize clinical decision and improve patient care.

Turning novel bacteria markers into non-invasive diagnostics

We developed one of the world’s first microbiome-based diagnostic products

to disrupt the diagnostic landscape of cancer diagnosis. Starting with one of the top killers globally, colorectal cancer, we have identified species-specific bacterial gene markers for early detection of colorectal cancer and adenomas. Our bacteria gene markers can detect colorectal cancer early, when it is most treatable and can also detect adenomas, helping to prevent cancer development.

Our
Technology Breakthrough 

We are revolutionizing disease detection through cutting-edge, non-invasive fecal microbiome diagnostics. Our proprietary technology harnesses novel microbial markers and advanced algorithms to predict disease risk with high accuracy—enabling early intervention and personalized care.

Developed by the Faculty of Medicine at The Chinese University of Hong Kong, our suite of diagnostic tests is based on metagenomic sequencing and tailored to diverse populations. Each test requires only a single stool sample and provides actionable dietary recommendations.

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Novel fecal microbial diagnostic solutions 

Three non-invasive fecal microbiome diagnostic tests targeting specific gut bacteria species have been developed by the Faculty of Medicine, Chinese University of Hong Kong. Early detection facilitates timely intervention and improves prognosis.

Non-invasive risk prediction test for Colorectal Cancer – M3CRC
World’s only fecal microbiome prediction test that detects non-advanced adenoma and recurrent adenoma with high sensitivity
94% sensitivity for CRC, as robust as colonoscopy
Sensitivity for adenoma is superior to currently available non-invasive tests
Up to 90% sensitivity to predict adenoma recurrence in subjects with a past history of adenomas
Non-invasive, just one stool sample is needed
Dietary recommendations are provided
Non-invasive risk prediction test for Autism Spectrum Disorder - MSX Metagenie™
WORLD'S FIRST non-invasive stool test to predict the risk of Autism Spectrum Disorder (ASD) in diverse populations
Comprehensive analysis of multi-kingdom microbial markers  
Achieved >85% sensitivity, >90% specificity
Non-invasive, just one stool sample is needed
Dietary recommendations are provided
Non-invasive risk prediction test for Inflammatory Bowel Disease - Enterosight®
WORLD'S FIRST non-invasive stool test to predict the risk of Inflammatory Bowel Disease (IBD) across ethnicities
Differentiates  inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) with high reliability
Achieved 88% sensitivity, 89% specificity for IBD
Non-invasive, just one stool sample is needed
Dietary recommendations are provided